The Influence of Quercetin on Some Parameters of Lipid Metabolism in Rats Chronically Exposed to Ammonium Fluoride

INTRODUCTION The aim of this work was to examine the influence of quercetin on chronic intoxication of rats with ammonium fluoride. A 1:1 mixture of quercetin 8,5' disulfonic acid sodium salts (Na2QDSA): NaQSA-5' and NaQSA-8 (Figure 1), synthesized at the Department of Inorganic Chemistry, Technical University of Rzeszów, was used. Pharmacological investigations have demonstrated the diverse activity of flavonoids, including rutin and its aglucon – quercetin.1,2 These compounds act as coenzymes, take part in cardiac carbohydrate metabolism, are helpful in the treatment of hypertension, slow down the process of atherosclerosis in blood vessels (Figure 1) and protect the liver from various harmful factors.3-5